Biomimetic systems

In order to study macromolecules of biological interest such as proteins or peptides, it is often needed to use model systems which properties are close to biological one. These models make interpretation of data easier and allow a better control of environmental conditions. The model systems we are particularly studying are lamellar phase, sponge phase, micelles, and liposomes.

Biomimetic systems made of lipids

Involved people: H. Benabdelhak (LIB), M. Waks (LIB), W. Urbach (LIB-ESN), P. Fuchs (Institut Jacques Monod)

Biomembrane are partially made of lipids. Thus, liposomes are incentively used as simplified model membranes. Our interested is to understand the mobility of lipids and proteins embedded in such simplified lipid bilayers.

Biomimetic systems made of surfactants

Involved people: H. Benabdelhak (LIB), M. Waks (LIB), W. Urbach (LIB-ESN), P. Fuchs (Institut Jacques Monod)

Surfactant offers a more accessible and wider range of stable bilayer structures (called micromemulsions, such as lamellar and sponge phases). These structures are also more stables toward changes in temperature and pH. We are studying and using such micromemulsions to understand the function of membrane proteins. We are particularly interested in micromemulsions made of nonionic sufactants CiEj.