Internship proposal: Ultrasound localization microscopy

Download the internship proposal

Internship type

  • Master 2 internship / last year of engineering school

Duration of the internship  

  • 6 months

Context

The internship is in the context of the European Contract ERC ResolveStroke (principal investigator Olivier Couture). The general objective of this contract is to create a new diagnostic tool for the early detection of stroke. Stroke is the second cause of mortality and the first cause of disability in the world. Through the use of super-resolution ultrasound (Couture et al., patent 2010, Errico et al. Nature 2015, Couture et al. IEEE UFFC 2018), we should be able to map the entire vascular system of a patient’s brain in a few minutes to define the presence of blockage (thrombus) or hemorrhage. Such approach could reduce significantly the mortality from stroke as it strongly depends on time.

The internship will be within the team Physiology and Pathology of the Microvasculature at the Laboratoire d’Imagerie Biomédicale (team leader: Olivier Couture). It is affiliated with the CNRS, INSERM and Sorbonne University and situated downtown Paris at the École de Médecine street (75006).

Objective

The objective of the internship is to develop new tools linked to the development of the new Stroke Scanner. This includes new approaches for detecting microbubbles inside blood vessels, new approaches to describe the anatomy and the physiology of the microvasculature, new tools to correct aberrations from the skull, along with new visualisation mechanism in 3D.

Mission(s)

The intern will have to acquire and process acoustic data to obtain super-resolved ultrasound images.

Competence

The intern should have a strong background in wave physics. A good proficiency in Matlab or other programming language is needed. A good English level is required. Competence in biology and/or medical sciences a plus.

Salary

Internship CNRS base salary

Contact

Olivier COUTURE, olivier.couture[at]sorbonne-universite.fr