Type de stage
- Stage de Master 2 ou dernière année d’école d’ingénieur
Date ou durée du stage
- 6 mois
Contexte
Bone diseases affect tens of millions of people across the world and create a significant burden in terms of healthcare costs. At present, mostly X-ray approaches are used to evaluate bone health in clinical settings. However, it is well accepted that X-ray based methods have limitations and they use ionizing radiations. Ultrasound (US) is a cheaper, safe and portable modality. It is the modality of choice for measuring children and is preferred in longitudinal clinical studies for ethical and safety reasons.
Quantitative ultrasound (US) imaging of cortical bone is an emerging research topic for which we are expecting rapid developments. Our group at LIB has recently obtained the first in vivo 2D images of the inside of cortical bone, enabling a measurement of bone thickness and speed of sound in bone.
Objectif
The current 2D imaging approach is limited to anatomical regions where bone resembles a hollow cylinder. The objective of this internship is to extend this work to 3D images. By doing so, anatomical regions of bone with complicated shapes could be imaged too. The goal is to develop an acquisition strategy and an algorithm for image reconstruction that accounts for refraction and anisotropic wave-speed in cortical bone.
Mission(s)
A fully programmable ultrasound system equipped with a matrix probe array (32×32 elements) will be used to acquire ultrasound echo signals on bone-shaped objects of known geometry. These objects are made of a bone-mimicking material with anisotropic elastic properties close to those of cortical bone. The student will be in charge of the experiments and the development of the algorithm for image reconstruction. This algorithm will be an adaptation of seismic imaging techniques.
Compétences
Master students in seismology or physical acoustics or students in school of engineering with a good understanding of wave physics will be considered. Basic programming skills (Matlab, C++) and writing skills (reports, research articles) are required. Excellent level of English is required
Rémunération
Gratifications de stage (Financial conditions follow Sorbonne Université guidelines)
Contact
Candidates are invited to contact Guillaume RENAUD (, Phone: +33 1 44 27 92 24) for additional information and to submit their application (including letter of motivation, CV, manuscript of first year of Master thesis, and name and contact information of two referees).
Applications will be considered until the end of January 2019 but prospective candidates should contact Guillaume RENAUD as soon as possible